Molecular Models

Discussion in 'General chat' started by MLGProGamer123, Jul 12, 2015.

  1. MLGProGamer123

    MLGProGamer123 Viva La Vida

    So, for a long time I've been into medicine and molecular biology. For obvious reasons, the two concepts are strongly associated with one another. Here is an insulin receptor.
    nUNP8s6.png
    In green is the receptor. The blue border you see is the cell membrane. In purple is insulin. Receptors are proteins incorporated into the cell membrane which transmit signals upon binding to its ligand. In the case of the insulin receptor, the ligand is insulin. Upon association of insulin and its receptor, the kinase domains (the two knobs you see below the membrane) activate each other. Upon activation, the kinase domains of the receptor activate other proteins, which in turn activate other proteins until finally the cell does something. This is called a signal cascade. Insulin induces a signal cascade that results in the cell presenting more glucose channel proteins in its membrane. In this way, insulin regulates sugar levels in the bloodstream. Here are other views:
    RlPsM1Ih.jpg
    At this angle, you can clearly see the insulin bound snuggly into a cavity in the insulin receptor. In blue is the membrane.
    g3C77NOh.jpg
    Here, you can see the symmetry of the receptor. It looks like an inverted V. The receptor is made up of two halves. Upon insulin binding, the halves come together to form the active dimer.

    Here is EcoRI. Not sure if you've heard of this in science, but EcoRI is a restriction enzyme. Restriction enzymes are molecular scissors made by bacteria that serve to cut foreign DNA from plasmids and 'restrict' infection by bacteriophages. EcoRI is shown in this figure in blue, with DNA in magenta and wheat color.
    7WPeOB6.png
    Here, EcoRI is bound tightly to the DNA. It is looking for a site which it will recognize and cut. Two parts of the enzyme fit in the small grooves of the DNA. EcoRI recognizes and cleaves at the sequence GAATTC. Another angle.
    GLHOT6j.png
    After the foreign DNA is removed, the original plasmid DNA is stuck back together by DNA Ligase, shown here in green.
    dpgpRHp.png 4uMUboa.png
    Aside from all that info, what do you guys think of the graphics, and images in general? Thanks for opinions. Will update soon.
     
    Last edited: Jul 12, 2015
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  2. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Hehe, they look like candy
     
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  3. cdennis02

    cdennis02 Forums Addict/OmegaAso

    You do belong in the medical field.
     
  4. EA_Sharks

    EA_Sharks New Member

    The black one has four holes and the white one has one hole.
     
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  5. MLGProGamer123

    MLGProGamer123 Viva La Vida

    Um which white and which black o.o
     
  6. EA_Sharks

    EA_Sharks New Member

    Ummmm. I think hydrogen is white and carbon is black.
     
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  7. MLGProGamer123

    MLGProGamer123 Viva La Vida

    Yea but which in the pictures?
     
  8. Grey

    Grey Trying to educate ajain and broomstick a bit

    The hell is this
     
  9. MLGProGamer123

    MLGProGamer123 Viva La Vida

    Look who doesn't read titles
     
  10. Cool
     
  11. TheD0ct0r

    TheD0ct0r ion know

    *Mind Blown*
     
  12. g_p

    g_p grondewa

    and this is a square:
    Unknown.jpeg
     
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  13. MLGProGamer123

    MLGProGamer123 Viva La Vida

    Oncology, Infectious Diseases, and Molecular Biology.
     
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  14. MLGProGamer123

    MLGProGamer123 Viva La Vida

    Thanks, you too!
     
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  15. Grey

    Grey Trying to educate ajain and broomstick a bit

    What's a title
     
    g_p likes this.
  16. g_p

    g_p grondewa

    tits le
     
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  17. Grey

    Grey Trying to educate ajain and broomstick a bit

    OH
     
  18. g_p

    g_p grondewa

    All has been revealed
     
  19. Grey

    Grey Trying to educate ajain and broomstick a bit

    :0 :-D
     
  20. BunnySlayah69

    BunnySlayah69 BunnehPvP

    @MLGProGamer123 you should start a Thread Teaching People about periodic elements and what they do and are used for lol
     
  21. Yummy

    Yummy Zlol13's brother

    Smh >.>
     
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  22. Stealthyyyy

    Stealthyyyy The God of Stealth

    Aluminum..
     
  23. Buritomaker

    Buritomaker New Member

    You learn that in year 8 as a mandatory course...
     
  24. smeags

    smeags Intentionally Philosophical

    Chemistry.
    I have mixed feelings for chemistry.
    Probably because I nearly blew myself up.
    But explosions.
     
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  25. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    I only use explosives or pyrotechnics when I intend to hurt myself. It's fun as all hell breaking loose when you need to put the fire on yourself out.
    Chemical explosions I am not fond of however, They leave a wicked sting after.
     
  26. smeags

    smeags Intentionally Philosophical

    Yeah, I really hate how I always forget to look away from magnesium when it's burning. x_x
    The white spots in my eyes afterward are ridiculous.
     
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  27. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Those white spots are normal for me, my eyes are messed up beyond repair.
     
  28. smeags

    smeags Intentionally Philosophical

    They're called cataracts. ;)
    Jk.
     
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  29. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Eh, I may have bad eye sight but it's from over exposure if anything.
     
  30. smeags

    smeags Intentionally Philosophical

    These cases are called TMH.
     
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  31. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Don't know what that is and Google has nothin for me
     
  32. smeags

    smeags Intentionally Philosophical

    That's because I just made it up on the spot.
    And before you ask, TMH is the unfortunate case of Too-Much-Hentai.
     
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  33. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Maybe so, but it actually happened due to some trauma I had during a storm as a child when lightning struck my home and the surge of electricity blew up something that was over my head in the hallway I was in, It was so bright and loud I lost those two senses for a couple of minutes and they slowly came back over the course of the next few hours, they haven't been the same since.
     
  34. smeags

    smeags Intentionally Philosophical

    How unfortunate for you.
     
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  35. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Nah, I like having bad eye sight and hearing. Gets people to not be bothered by me listening to music and ignoring them because they know I can barely hear them either way.
     
  36. smeags

    smeags Intentionally Philosophical

    There are pros and cons to both.
     
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  37. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Only con I can think of is that whenever a girl is calling me their voices are too soft for me to hear.
     
  38. smeags

    smeags Intentionally Philosophical

    Con: If someone is sneaking up on you, it's harder to detect.
    Glasses probably needed later in life.
     
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  39. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    I can feel when someone is approaching me, I start to hear a high pitched whistle when someone is close for some annoying reason.
    Now that I think about it, it isn't much of a con because they tend to have to physically grab me to get my attention and that ain't so bad ;)
     
  40. smeags

    smeags Intentionally Philosophical

    Lol.

    Oh you.
     
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  41. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    Put a sock in it
     
  42. smeags

    smeags Intentionally Philosophical

    ( ͡~ ͜ʖ ͡°)
     
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  43. Lostvayne

    Lostvayne I'll dance alone tonight Staff Member Mod

    That looks rather creepy
     

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